X-RAY Crystallography

Sector 21 at the APS Synchrotron at Argonne National Laboratory is being developed into a dual-beamline facility with 4 experimental stations that will serve Michigan researchers seeking to determine x-ray structures at the highest level of resolution available by any crystallographic technique. Access to the synchrotron by Michigan researchers has already increased with the opening of the 21ID-D station in December 2006. After the Dedication and Ribbon Cutting Ceremony on May, 11, 2007, the 21ID-F and 21ID-F stations will become operational. The new facility is expected to operate at full capacity by the end of 2007 when the 21ID-E station comes on line.

Facilities for the analysis of protein and nucleic acid crystals are available also are available at all the MCSB sites (UM, MSU, WSU and VARI).

 Cytochrome c oxidase single crystal

New technology available soon :

MarMosaic CCD Detectors

  • The MarMosaic series of detectors use 3 x 3 or 4 x 4 arrays of tiled fiber optic taper elements to make a very large active area for detection. The images produced have no inactive strips between each of the fiber optic tapers. LS-CAT will install MarMosaic 300 detectors in the 21ID-D and 21ID-E stations and MarMosaic 225 detectors in the 21ID-F and 21ID-G stations. Theses CCD detectors will be paired with MD2 microdiffractometers from EMBL/ESRF.

For more information, contact Matt Larson
Copyright Michigan Center for Structural Biology, 2007
updated 04/07

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